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Some metabolic improvements observed during treatment may also shift back toward baseline over time, although this is also dependent on dietary and lifestyle behaviours
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The time to reach maximum concentration (Tmax) was significantly prolonged in the microneedle group (18.24 5.26 h) compared with the hydrogel group (7.32 0.21 h), suggesting a more sustained release profile
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TRT has direct metabolic effects, including: Muscle growth : Testosterone directly stimulates muscle protein synthesis, growth, and repair, especially of the fast-twitch muscle fibers that power strength and hypertrophy, says Lee
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